Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028699 | 0.84 | MEN1 (0.39) | MAPTCHEK1AURKACSNK1A1CDK8 | |
| SCHEMBL29028696 | 0.84 | CSNK2A1 (0.40) | MAPTCHEK1AURKACSNK1A1CDK8 | |
| SCHEMBL29028719 | 0.83 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29028700 | 0.83 | MPO (0.47) | MAPTKDM4EMAPK1ALDH1A1HPGD | |
| SCHEMBL29028720 | 0.83 | ADORA3 (0.40) | MAPTRXFP1GRM4 | |
| SCHEMBL29028776 | 0.81 | MPO (0.42) | DYRK1AKDM4EPDE10AGRM4MAPK1 | |
| SCHEMBL29028704 | 0.76 | MEN1 (0.45) | MAPTKDM4ERXFP1PDE10AMAPK1 | |
| SCHEMBL29028803 | 0.76 | ALDH1A1 (0.41) | MAPTCLK4KDM4EPDE10AMAPK1 | |
| SCHEMBL29028680 | 0.72 | NPC1 (0.43) | MAPTKDM4EALDH1A1PDPK1NPC1 | |
| SCHEMBL29028787 | 0.72 | MAPT (0.46) | MAPTKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |