Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028711 | 1.00 | MPO (0.55) | MPOIDO1TDO2FGFR1DAPK3 | |
| SCHEMBL29028724 | 0.85 | SMN1; SMN2 (0.46) | MPOIDO1TDO2CNR1SMN1; SMN2 | |
| SCHEMBL29028700 | 0.84 | MPO (0.47) | MPOSMN1; SMN2ALDH1A1GAAHTT | |
| SCHEMBL29028769 | 0.84 | GRM5 (0.41) | MPOALDH1A1HTTLMNAABCG2 | |
| SCHEMBL30473327 | 0.84 | MEN1 (0.41) | MPOCNR1ALDH1A1LMNAABCG2 | |
| SCHEMBL29028782 | 0.84 | LMNA (0.51) | MPOIDO1TDO2ALDH1A1HTT | |
| SCHEMBL29028775 | 0.84 | MEN1 (0.41) | MPOCNR1ALDH1A1LMNAABCG2 | |
| SCHEMBL29028720 | 0.84 | ADORA3 (0.40) | MPOIDO1TDO2RXFP1HTT | |
| SCHEMBL29028803 | 0.83 | ALDH1A1 (0.41) | MPOSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL29028699 | 0.83 | MEN1 (0.39) | MPOFGFR1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |