Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425811 | 0.81 | HCAR3 (0.44) | ALDH1A1KDM4EHCAR3MAPTVCAM1 | |
| SCHEMBL29029076 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHCAR3MAPTVCAM1 | |
| SCHEMBL1918935 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EVCAM1SMN1; SMN2HTT | |
| SCHEMBL31208163 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4EHCAR3MAPTVCAM1 | |
| SCHEMBL30911641 | 0.75 | POLB (0.39) | ALDH1A1KDM4EHTTPOLB | |
| SCHEMBL2178150 | 0.72 | HCAR3 (0.37) | ALDH1A1KDM4EHCAR3MAPTVCAM1 | |
| SCHEMBL2186033 | 0.72 | PIN1 (0.38) | ALDH1A1KDM4EMAPTVCAM1SMN1; SMN2 | |
| SCHEMBL29029075 | 0.71 | VCAM1 (0.37) | ALDH1A1KDM4EVCAM1HTTMEN1 | |
| SCHEMBL19064107 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTVCAM1SMN1; SMN2 | |
| SCHEMBL5697784 | 0.70 | ALDH1A1 (0.69) | ALDH1A1KDM4EHCAR3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |