Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PTAFR | P25105 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2797809 | 0.87 | SIRT1 (0.44) | KMT2AMEN1PTPN1ALDH1A1HPGD | |
| SCHEMBL9246592 | 0.84 | CDK1 (0.44) | PTAFRACHEALDH1A1KDM4E | |
| SCHEMBL5180445 | 0.75 | ELANE (0.51) | KMT2AMEN1PTGS2ALDH1A1KDM4E | |
| SCHEMBL11678651 | 0.73 | HSD11B1 (0.46) | KMT2AMEN1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3229576 | 0.70 | ELANE (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8104489 | 0.68 | SIRT1 (0.40) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11101046 | 0.66 | ACHE (0.58) | KMT2AMEN1PTAFRACHEPTPN1 | |
| SCHEMBL11503879 | 0.66 | MEN1 (0.56) | KMT2AMEN1PTAFRACHEPTPN1 | |
| SCHEMBL7351311 | 0.65 | NFKB1 (0.57) | KMT2AMEN1PTAFRACHEPTPN1 | |
| SCHEMBL13414990 | 0.64 | ACHE (0.54) | KMT2AMEN1PTAFRACHEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747773-B1 | Photostable organic sunscreen compositions with antioxidant properties | MERCK PATENT GMBH (DE) | 2010-08-04 | — | — | EP | disclosed |
| EP-1952843-A1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | Merck Patent GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| EP-1406582-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | disclosed |