Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | CTSE | P14091 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144130 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LMNATP53SMN1; SMN2POLB | |
| SCHEMBL7342248 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL7342254 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL28294340 | 0.84 | KMT2A (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL11144113 | 0.83 | LMNA (0.40) | ALDH1A1LMNATP53SMN1; SMN2HDAC3 | |
| SCHEMBL6464595 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL7345170 | 0.83 | MMP2 (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL11140560 | 0.82 | HDAC3 (0.40) | ALDH1A1LMNATP53SMN1; SMN2HDAC3 | |
| SCHEMBL6535237 | 0.82 | SMN1; SMN2 (0.41) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL11149216 | 0.81 | HDAC3 (0.42) | ALDH1A1LMNATP53SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116429952-B | Depression marker, application thereof in depression diagnosis and evaluation device | 深圳市第二人民医院(深圳市转化医学研究院) | 2024-02-02 | — | — | CN | disclosed |
| CN-116429952-A | Depression marker, application thereof in depression diagnosis and evaluation device | 深圳市第二人民医院(深圳市转化医学研究院) | 2023-07-14 | — | — | CN | disclosed |