Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342254 | 1.00 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL6464595 | 0.98 | ALDH1A1 (0.39) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL7345170 | 0.98 | MMP2 (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL28294340 | 0.88 | KMT2A (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL7345167 | 0.87 | LMNA (0.37) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL6535237 | 0.85 | SMN1; SMN2 (0.41) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL757884 | 0.84 | TP53 (0.48) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL29033834 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL8429495 | 0.84 | LMNA (0.39) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL8429588 | 0.84 | LMNA (0.39) | ALDH1A1LMNATP53SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088615-A | Detection and quantitative mass spectrometric determination method for renal function metabolin | 梅塔博隆股份有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-106714556-A | Methods and systems for determining risk of autism spectrum disorders | 美国控股实验室公司 | 2017-05-24 | — | — | CN | claimed |
| CN-105209909-A | Biomarkers associated with renal function and methods of use thereof | METABOLON INC | 2015-12-30 | — | — | CN | claimed |
| EP-3616721-B1 | BLOOD PURIFICATION BY ALKALINIZING AGENT | UNIV TOHOKU (JP) | 2024-12-04 | — | — | EP | disclosed |
| CN-113970606-B | Metabolic markers for diagnosing attention deficit hyperactivity disorder syndrome in urine of children | 首都医科大学附属北京儿童医院 | 2022-06-14 | — | — | CN | disclosed |
| CN-113970606-A | Metabolic markers for diagnosing attention deficit hyperactivity disorder syndrome in urine of children | 首都医科大学附属北京儿童医院 | 2022-01-25 | — | — | CN | disclosed |
| US-20210389331-A1 | Method for Diagnosing Intermittent Claudication and Chronic Limb-Threatening Ischemia | UNIV MCMASTER (CA) | 2021-12-16 | — | — | US | disclosed |
| EP-3918603-A1 | PREDICTING BLOOD METABOLITES | Yeda Research and Development Co. Ltd (IL) | 2021-12-08 | — | — | EP | disclosed |
| US-20210315816-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-14 | — | — | US | disclosed |
| WO-2021113989-A1 | METHOD OF DIAGNOSING AND TREATMENT MONITORING OF CROHN'S DISEASE AND ULCERATIVE COLITIS | MCMASTER UNIVERSITY (CA) | 2021-06-17 | — | — | WO | disclosed |
| US-20210121426-A1 | BLOOD PURIFICATION BY ALKALINIZING AGENT | TOHOKU UNIVERSITY (JP) | 2021-04-29 | — | — | US | disclosed |
| CN-101272763-A | Process for preparation of liquid dosage form containing sodium 4-phenylbutyrate | NAVINTA LLC (US) | 2008-09-24 | — | — | CN | disclosed |
| CN-1343489-A | Novel percutaneous absorption dosage form of medicine for resisting cancer and inhibiting cell hyperproliferation or poor differentiation | ZHONG YILIN (CN) | 2002-04-10 | — | — | CN | disclosed |
| EP-0500905-A1 | PHARMACEUTICAL COMPOSITIONS FOR USE IN TREATING AIDS. | BURZYNSKI STANISLAW R (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1992004027-A1 | PHARMACEUTICAL COMPOSITIONS FOR USE IN TREATING AIDS | BURZYNSKI STANISLAW R (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0069232-B1 | PHARMACEUTICAL COMPOSITION COMPRISING PHENYL ACETYL GLUTAMINE,A COMBINATION OF THIS COMPOUND WITH PHENYLACETIC ACID OR 3-(PHENYLACETYLAMINO)PIPERIDINE-2,6-DIONE,A PROCESS FOR ISOLATING THE LATTER FROM URINE AND A PROCESS FOR THE SYNTHESIS OF 3-(PHENYLACETYLAMINO)PIPERIDINE-2,6-DIONE | BURZYNSKI, Stanislaw R. (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4559325-A | ANTITUMOR AGENTS | BURZYNSKI STANISLAW R (US) | 1985-12-17 | — | — | US | disclosed |
| US-4558057-A | URINE EXTRACTS | BURZYNSKI STANISLAW R (US) | 1985-12-10 | — | — | US | disclosed |
| US-4470970-A | ANTITUMOR AND-CARCINOGENIC AGENT EXTRACTED FROM URINE | BURZYNSKI STANISLAW R | 1984-09-11 | — | — | US | disclosed |
| EP-0069232-A2 | Pharmaceutical composition comprising phenyl acetyl glutamine,a combination of this compound with phenylacetic acid or 3-(phenylacetylamino)piperidine-2,6-dione,a process for isolating the latter from urine and a process for the synthesis of 3-(phenylacetylamino)piperidine-2,6-dione | BURZYNSKI, Stanislaw R. (US) | 1983-01-12 | — | — | EP | disclosed |