Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757884 | 0.90 | TP53 (0.48) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL8429588 | 0.87 | LMNA (0.39) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL8429495 | 0.87 | LMNA (0.39) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL7342248 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL7342254 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL28294340 | 0.85 | KMT2A (0.40) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL6464595 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL7345170 | 0.84 | MMP2 (0.40) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL29033834 | 0.82 | ALDH1A1 (0.40) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A | |
| SCHEMBL27960539 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2TP53ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052968-A4 | $g(a)-AMIDES OF $i(L)-AMINO ACIDS AS FRAGRANCE PRECURSORS | GILLETTE CO (US) | 2004-09-15 | — | — | EP | claimed |
| EP-1052968-A1 | $g(a)-AMIDES OF $i(L)-AMINO ACIDS AS FRAGRANCE PRECURSORS | THE GILLETTE COMPANY (US) | 2000-11-22 | — | — | EP | claimed |
| WO-1999030680-A1 | α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS | THE GILLETTE COMPANY (US) | 1999-06-24 | — | — | WO | claimed |