Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500034 | 0.74 | SIGMAR1 (0.31) | SIGMAR1SMN1; SMN2 | |
| SCHEMBL15524924 | 0.66 | OPRM1 (0.38) | HDAC1HDAC2MEN1NPC1RAB9A | |
| SCHEMBL8205801 | 0.66 | CHRNB2 (0.35) | HDAC1HDAC2MEN1NPC1RAB9A | |
| SCHEMBL8205885 | 0.60 | CHRNB2 (0.37) | NPC1OPRM1OPRK1OPRL1 | |
| SCHEMBL11749210 | 0.58 | POLB (0.43) | HDAC1HDAC2OPRM1OPRK1OPRL1 | |
| SCHEMBL444478 | 0.57 | ALDH1A1 (0.53) | MEN1NPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL10339222 | 0.56 | HDAC1 (0.38) | HDAC1HDAC2MEN1NPC1RAB9A | |
| Biphenyl SCHEMBL28098924 | 0.55 | ALDH1A1 (0.90) | NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL9488195 | 0.55 | OPRM1 (0.36) | OPRM1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL7107009 | 0.55 | ALDH1A1 (0.50) | MEN1NPC1RAB9AKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806142-B1 | Method for the production of (poly)peptides by using truncated variants of the SV 40 large T antigen with an intact N terminus | RHEIN BIOTECH PROZ & PROD GMBH (DE) | 2010-07-14 | — | — | EP | disclosed |
| EP-1806142-A1 | Method for the production of (poly)peptides by using truncated variants of the SV 40 large T antigen with an intact N terminus | VaDeCo Biotech GmbH & Co. KG (DE) | 2007-07-11 | — | — | EP | disclosed |
| EP-1117803-B1 | METHOD FOR THE PRODUCTION OF (POLY)PEPTIDES BY USING TRUNCATED VARIANTS OF THE SV40 LARGE T ANTIGEN WITH AN INTACT N TERMINUS | VADECO BIOTECH GMBH & CO KG (DE) | 2006-12-13 | — | — | EP | disclosed |
| EP-1117803-A1 | METHOD FOR THE PRODUCTION OF (POLY)PEPTIDES BY USING TRUNCATED VARIANTS OF THE SV40 LARGE T ANTIGEN WITH AN INTACT N TERMINUS | REIMANN, Hansjurg (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020606-A1 | METHOD FOR THE PRODUCTION OF (POLY)PEPTIDES BY USING TRUNCATED VARIANTS OF THE SV40 LARGE T ANTIGEN WITH AN INTACT N TERMINUS | REIMANN HANSJOERG (DE) | 2000-04-13 | — | — | WO | disclosed |