Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506166 | 0.82 | GPR119 (0.51) | FAAHMAPTLMNAMEN1KMT2A | |
| SCHEMBL12490134 | 0.80 | FAAH (0.47) | FAAHMAPTLMNAMEN1KMT2A | |
| SCHEMBL12490987 | 0.77 | FAAH (0.50) | FAAHMAPTLMNATHRBHTT | |
| SCHEMBL27814281 | 0.77 | HTT (0.58) | FAAHMAPTLMNAKDM4EHTT | |
| SCHEMBL4227209 | 0.77 | NOTUM (0.44) | FAAHLMNAHSD11B1 | |
| SCHEMBL17115053 | 0.76 | FAAH (0.48) | FAAHKMT2APOLBALDH1A1HTT | |
| SCHEMBL20116402 | 0.75 | MAPT (0.58) | FAAHMAPTLMNATP53THRB | |
| SCHEMBL20116655 | 0.74 | SMN1; SMN2 (0.54) | MAPTLMNAMEN1KMT2ATP53 | |
| SCHEMBL8271752 | 0.74 | LMNA (0.46) | FAAHLMNAPOLBALDH1A1HSD11B1 | |
| SCHEMBL4234552 | 0.74 | SMN1; SMN2 (0.48) | FAAHMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |