Acetaminophen Mercapturate

Acetaminophen Mercapturate

SCHEMBL29048126

CC(=O)Nc1ccc(O)c(SCC(N)C(=O)O)c1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.42
▸ KDM4E B2RXH2 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ EGFR P00533 1/20 0.41
▸ LCK P06239 1/20 0.41
▸ FYN P06241 1/20 0.41
▸ ADORA3 P0DMS8 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ PTGS1 P23219 1/20 0.41
▸ HTR2A P28223 1/20 0.41
▸ PTGS2 P35354 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ SLC7A5 Q01650 1/20 0.41
▸ HIF1A Q16665 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ CASR P41180 3/20 0.41
▸ PKM P14618 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetaminophen Mercapturate SCHEMBL30547299 1.00 POLB (0.42) POLBKDM4EUSP2EGFRLCK
Acetaminophen Mercapturate SCHEMBL3454308 1.00 POLB (0.42) POLBKDM4EUSP2EGFRLCK
SCHEMBL27075586 0.83 PRNP (0.48) POLBKDM4EPKMGAASMN1; SMN2
SCHEMBL10925710 0.80 PTGS1 (0.52) PTGS1
SCHEMBL31065560 0.79 GAA (0.60) POLBUSP2HSD17B10TDP1GAA
SCHEMBL14003929 0.79 KIF11 (0.46) POLBKDM4EUSP2EGFRLCK
SCHEMBL14003924 0.79 KIF11 (0.46) POLBKDM4EUSP2EGFRLCK
SCHEMBL17164719 0.76 CASR (0.41) POLBKDM4EUSP2EGFRLCK
SCHEMBL29831751 0.76 POLB (0.39) POLBKDM4EPKMGAASMN1; SMN2
SCHEMBL5024800 0.74 USP2 (0.54) POLBKDM4EUSP2EGFRLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOC DES PRODUITS NESTLE S A (CH) 2026-05-21 — — US claimed
US-20250281438-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-09-11 — — US claimed
CN-116546981-A Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof and at least one thymol and/or carvacrol 雀巢产品有限公司 2023-08-04 — — CN claimed
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOC DES PRODUITS NESTLE S A (CH) 2026-05-21 — — US disclosed
US-20250281438-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL SOCIETE DES PRODUITS NESTLE S.A. (CH) 2025-09-11 — — US disclosed
CN-116546981-A Compositions and methods using at least one glycine or derivative thereof and/or at least one N-acetylcysteine or derivative thereof and at least one thymol and/or carvacrol 雀巢产品有限公司 2023-08-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137643-A1 COMPOSITIONS AND METHODS USING AT LEAST ONE GLYCINE OR DERIVATIVE THEREOF AND/OR AT LEAST ONE N-ACETYLCYSTEINE OR DERIVATIVE THEREOF, AND AT LEAST ONE THYMOL AND/OR CARVACROL LIPC, GGT1, TGM2 POLB 1613/4885KDM4E 4438/4885USP2 2203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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