Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29058642 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPK1LMNAMMP1MMP9 | |
| SCHEMBL29761324 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTMAPK1LMNAMMP1 | |
| SCHEMBL20522633 | 0.81 | ALDH1A1 (0.41) | SMN1; SMN2MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL29058598 | 0.79 | LMNA (0.32) | SMN1; SMN2MAPTLMNAMMP1MMP9 | |
| SCHEMBL29761331 | 0.77 | MMP1 (0.34) | SMN1; SMN2MAPTMAPK1LMNAMMP1 | |
| SCHEMBL29761328 | 0.76 | POLB (0.35) | SMN1; SMN2LMNANPSR1MEN1KMT2A | |
| SCHEMBL20522637 | 0.76 | NPEPPS (0.37) | SMN1; SMN2LMNAHPGDNPSR1MEN1 | |
| SCHEMBL29058623 | 0.74 | ALDH1A1 (0.37) | MAPK1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL29761332 | 0.74 | ALDH1A1 (0.37) | MAPK1LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL29761330 | 0.74 | ALDH1A1 (0.37) | MAPK1LMNAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267556-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-116635386-A | Substituted pyridazinone herbicides | FMC公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022140309-A1 | SUBSTITUTED PYRIDAZINONE HERBICIDES | FMC CORPORTION (US) | 2022-06-30 | — | — | WO | disclosed |