SCHEMBL29761324

SCHEMBL29761324

CC(=O)OCOc1c(Cl)nn(C)c(=O)c1-c1c(C)ccc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.37
▸ LMNA P02545 3/20 0.36
▸ MMP1 P03956 1/20 0.36
▸ MMP9 P14780 1/20 0.36
▸ MMP8 P22894 1/20 0.36
▸ HPGD P15428 2/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ NPBWR1 P48145 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ TP53 P04637 1/20 0.34
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29058598 0.89 LMNA (0.32) SMN1; SMN2LMNAMMP1MMP9MMP8
SCHEMBL29058636 0.89 SMN1; SMN2 (0.37) SMN1; SMN2LMNAMMP1MMP9MMP8
SCHEMBL29058642 0.84 SMN1; SMN2 (0.38) SMN1; SMN2LMNAMMP1MMP9MMP8
SCHEMBL21835495 0.82 NPBWR1 (0.41) SMN1; SMN2LMNAMMP1MMP9MMP8
SCHEMBL29382816 0.82 NPBWR1 (0.41) SMN1; SMN2LMNAMMP1MMP9MMP8
SCHEMBL26163609 0.82 SMN1; SMN2 (0.40) SMN1; SMN2LMNAMMP1MMP9MMP8
SCHEMBL25202984 0.78 HPGD (0.38) SMN1; SMN2HPGDMEN1KMT2AMAPT
SCHEMBL21835458 0.78 HSD11B1 (0.38) SMN1; SMN2HPGDMEN1KMT2ANPBWR1
SCHEMBL29383185 0.78 HSD11B1 (0.38) SMN1; SMN2HPGDMEN1KMT2ANPBWR1
SCHEMBL29761330 0.73 ALDH1A1 (0.37) LMNAHPGDMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267556-B1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORP (US) 2025-04-09 — — EP claimed
EP-4267556-A1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORPORATION (US) 2023-11-01 — — EP claimed
CN-116635386-A Substituted pyridazinone herbicides FMC公司 2023-08-22 — — CN claimed
WO-2022140309-A1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORPORTION (US) 2022-06-30 — — WO claimed
EP-4267556-A1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORPORATION (US) 2023-11-01 — — EP disclosed
WO-2022140309-A1 SUBSTITUTED PYRIDAZINONE HERBICIDES FMC CORPORTION (US) 2022-06-30 — — WO disclosed
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