Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28409371 | 0.96 | ALDH1A1 (0.33) | ALDH1A1LMNA | |
| SCHEMBL27427767 | 0.77 | TSHR (0.41) | — | |
| SCHEMBL15099704 | 0.75 | LMNA (0.38) | ALDH1A1LMNAPSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL35525 | 0.73 | MAPT (0.50) | ALDH1A1LMNAPSMD14PLA2G1BMMP2 | |
| SCHEMBL14958465 | 0.73 | LMNA (0.47) | ALDH1A1LMNAPSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL1405424 | 0.73 | LMNA (0.47) | ALDH1A1LMNAPSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL9819532 | 0.73 | MAPT (0.50) | ALDH1A1LMNAPSMD14PLA2G1BMMP2 | |
| Hydrochloric Acid SCHEMBL4774500 | 0.73 | CYP3A4 (0.42) | LMNAPSMD14PLA2G1BMMP2RAD52 | |
| SCHEMBL15096146 | 0.73 | LMNA (0.36) | ALDH1A1LMNA | |
| SCHEMBL2841245 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707804-B | Composite polypropylene electret material and preparation method and application thereof | 联泓(江苏)新材料研究院有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-115707804-B | Composite polypropylene electret material and preparation method and application thereof | 联泓(江苏)新材料研究院有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116685052-A | Conductive silver paste special for glass-based circuit board | 智玻蓝芯(福建)光电科技有限公司 | 2023-09-01 | — | — | CN | disclosed |