Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848691 | 0.98 | MEN1 (0.38) | CYP3A4SLC5A7MEN1LMNAKMT2A | |
| Bromide SCHEMBL5713154 | 0.95 | MEN1 (0.42) | CYP3A4SLC5A7MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL27626657 | 0.73 | DNM1 (0.50) | KMT2APLA2G1BRAD52ATG4BDNM1 | |
| Hydrochloric Acid SCHEMBL29061502 | 0.73 | ALDH1A1 (0.33) | LMNAPSMD14PLA2G1BMMP2RAD52 | |
| SCHEMBL27427767 | 0.71 | TSHR (0.41) | — | |
| SCHEMBL901753 | 0.71 | — | — | |
| SCHEMBL4788386 | 0.70 | MEN1 (0.39) | CYP3A4SLC5A7MEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL20163202 | 0.69 | CYP3A4 (0.50) | CYP3A4SLC5A7MEN1LMNAKMT2A | |
| SCHEMBL5804103 | 0.68 | MEN1 (0.38) | CYP3A4SLC5A7MEN1LMNAKMT2A | |
| Bromide SCHEMBL28409371 | 0.68 | ALDH1A1 (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11883514-B2 | Stable low pH personal care compositions and methods for the same | COLGATE-PALMOLIVE COMPANY (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2023144809-A1 | ANTIMICROBIAL NATURAL COMPOSITIONS | BIO-ACTIVES SYNERGIO LTD (IL) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144808-A1 | ANTIMICROBIAL COMPOSITIONS | BIO-ACTIVES SYNERGIO LTD (IL) | 2023-08-03 | — | — | WO | disclosed |
| US-20220202673-A1 | Silicone-Free Personal Care Compositions and Methods for the Same | COLGATE-PALMOLIVE COMPANY (US) | 2022-06-30 | — | — | US | disclosed |
| EP-4017455-A1 | STABLE LOW pH PERSONAL CARE COMPOSITIONS AND METHODS FOR THE SAME | Colgate-Palmolive Company (US) | 2022-06-29 | — | — | EP | disclosed |
| CN-107913194-B | Ultraviolet radiation absorbing polymer composition | 强生消费者公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114599334-A | Stable low pH personal care compositions and methods therefor | 高露洁-棕榄公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-109790286-B | Ultraviolet radiation absorbing polymer composition | 巴斯夫欧洲公司 | 2022-04-12 | — | — | CN | disclosed |
| US-20210128430-A1 | STABLE LOW pH PERSONAL CARE COMPOSITIONS AND METHODS FOR THE SAME | COLGATE-PALMOLIVE COMPANY | 2021-05-06 | — | — | US | disclosed |
| WO-2021086403-A1 | STABLE LOW pH PERSONAL CARE COMPOSITIONS AND METHODS FOR THE SAME | COLGATE-PALMOLIVE COMPANY (US) | 2021-05-06 | — | — | WO | disclosed |
| CN-1387429-A | Product structured compositions for personal care formulations | ISP INVESTMENTS INC (US) | 2002-12-25 | — | — | CN | disclosed |
| EP-1212042-A1 | PRODUCT-STRUCTURANT COMPOSITION FOR PERSONAL CARE FORMULATIONS | ISP INVESTMENTS INC. (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6368607-B1 | MULTILAYER LAMELLAR GEL | ISP INVESTMENTS INC. | 2002-04-09 | — | — | US | disclosed |
| WO-2001019343-A1 | PRODUCT-STRUCTURANT COMPOSITION FOR PERSONAL CARE FORMULATIONS | ISP INVESTMENTS INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| WO-2000019968-A1 | COSMETIC COMPOSITION FOR REJUVENATION OF SKIN WITHOUT SKIN IRRITATION | ISP INVESTMENTS INC. (US) | 2000-04-13 | — | — | WO | disclosed |
| US-5637296-A | TERPOLYMER OF V-VINYLPYRROLIDONE, N-VINYLCAPROLACTAM AND AMINOALKYL (METH)ACRYLATE | ISP INVESTMENTS INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5627149-A | PERSONAL CARE PRODUCT WITH ANIONIC AND CATIONIC SURFACTANT FOR HAIR OR SKIN COSMETICS | COLGATE PALMOLIVE COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| US-5576280-A | INCREASES HARDNESS OF BAR | COLGATE-PALMOLIVE COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0708175-A1 | Composition | Colgate-Palmolive Company (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1996006592-A1 | LOW VOC HAIR SPRAY RESIN COMPOSITION OF IMPROVED SPRAY PROPERTIES | ISP INVESTMENTS INC. (US) | 1996-03-07 | — | — | WO | disclosed |