Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930874 | 0.84 | KMT2A (0.58) | KMT2APTGS2MAPTPOLBPKM | |
| SCHEMBL28112129 | 0.84 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EHTT | |
| SCHEMBL28797061 | 0.84 | ALDH1A1 (0.45) | KMT2AMAPTPOLBPKMALDH1A1 | |
| SCHEMBL27648019 | 0.81 | BCL9 (0.59) | KMT2APTGS2MAPTPOLBPKM | |
| SCHEMBL29065053 | 0.80 | ACHE (0.41) | KMT2APTGS2MAPTALDH1A1KDM4E | |
| SCHEMBL27825837 | 0.79 | PTGS2 (0.50) | KMT2APTGS2MAPTPOLBPKM | |
| SCHEMBL2592352 | 0.77 | LMNA (0.57) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5842867 | 0.77 | LMNA (0.56) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL1930857 | 0.77 | MAPT (0.74) | KMT2APTGS2MAPTPOLBPKM | |
| Sulfuric Acid SCHEMBL9110029 | 0.76 | ELANE (0.44) | KMT2AMAPTPKMALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710430-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2023-09-05 | — | — | CN | disclosed |