Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973539 | 0.80 | TRPA1 (0.44) | TPSAB1TPSD1TPSG1SMN1; SMN2MEN1 | |
| SCHEMBL28496076 | 0.80 | SMN1; SMN2 (0.43) | TPSAB1TPSD1TPSG1SMN1; SMN2MEN1 | |
| SCHEMBL28864238 | 0.76 | ALDH1A1 (0.51) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL24253974 | 0.75 | SMN1; SMN2 (0.45) | TPSAB1TPSD1TPSG1SMN1; SMN2MEN1 | |
| SCHEMBL1982867 | 0.74 | KDM4E (0.47) | NOS1NOS2SMN1; SMN2MAPTHTT | |
| SCHEMBL30950209 | 0.72 | ALDH1A1 (0.44) | TPSAB1TPSD1TPSG1SMN1; SMN2MEN1 | |
| SCHEMBL30595900 | 0.71 | ADRB1 (0.55) | MEN1KMT2ATSHRMGLL | |
| SCHEMBL28786999 | 0.71 | LMNA (0.53) | MEN1KMT2ATSHRMGLL | |
| SCHEMBL14740643 | 0.70 | ALDH1A1 (0.56) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL653157 | 0.70 | CYP1A2 (0.67) | TPSAB1TPSD1TPSG1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566102-B | Substituted pyrrolopyridines as activin receptor-like kinase inhibitors | 缆图药品公司 | 2023-09-08 | — | — | CN | disclosed |