Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607913 | 0.78 | P2RX7 (0.40) | EPHX2P2RX7CNR2HSD11B1LMNA | |
| SCHEMBL12040557 | 0.75 | LMNA (0.57) | EPHX2P2RX7CNR2MAOBMAOA | |
| SCHEMBL6901742 | 0.71 | HSD11B1 (0.57) | EPHX2P2RX7SIGMAR1CNR2MAOB | |
| SCHEMBL8581921 | 0.70 | CNR2 (0.63) | EPHX2P2RX7P2RX2CNR2MEN1 | |
| SCHEMBL8064643 | 0.70 | MEN1 (0.50) | EPHX2P2RX2SIGMAR1CNR2SMN1; SMN2 | |
| SCHEMBL22027031 | 0.70 | LMNA (0.40) | P2RX7CNR2MAOBMAOAHSD11B1 | |
| SCHEMBL24241924 | 0.70 | MEN1 (0.45) | CNR2MAOBMAOAHSD11B1LMNA | |
| SCHEMBL3844883 | 0.70 | GAA (0.37) | EPHX2P2RX7CNR2HSD11B1LMNA | |
| SCHEMBL29287201 | 0.70 | MEN1 (0.45) | CNR2MAOBMAOAHSD11B1LMNA | |
| SCHEMBL16352314 | 0.69 | LMNA (0.56) | MAOBMAOAHSD11B1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | claimed |
| CN-116444438-B | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2024-02-13 | — | — | CN | disclosed |
| CN-116789600-A | Preparation method and application of novel tetrahydroindazole antitumor compound | 深圳市人民医院 | 2023-09-22 | — | — | CN | disclosed |
| CN-116444438-A | Benzamide compound and preparation method, using method and application thereof | 深圳市人民医院 | 2023-07-18 | — | — | CN | disclosed |