Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523786 | 0.84 | ELANE (0.38) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL7523253 | 0.82 | FAAH (0.45) | MEN1KMT2AFAAHEPHX2 | |
| SCHEMBL8064644 | 0.79 | KDM1A (0.46) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL27549150 | 0.75 | KDM1A (0.57) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL5475255 | 0.71 | HSD11B1 (0.44) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL29065708 | 0.70 | EPHX2 (0.47) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL21002189 | 0.69 | KDM1A (0.49) | MEN1KMT2AFAAHCNR2KDM1A | |
| SCHEMBL30791157 | 0.69 | KDM1A (0.49) | MEN1KMT2AFAAHCNR2KDM1A | |
| SCHEMBL7523248 | 0.68 | EPHX2 (0.43) | MEN1KMT2AFAAHCNR2EPHX2 | |
| SCHEMBL31609059 | 0.68 | KDM1A (0.45) | MEN1KMT2AFAAHCNR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000001450-A | SYNTHESIS OF INTERMEDIATE OF 1,2-DIOXETANES | TROPIX INC | 2000-01-07 | — | — | JP | disclosed |