Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11498896 | 0.78 | LMNA (0.46) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL11551633 | 0.74 | ALDH1A1 (0.40) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL11296841 | 0.74 | MAOA (0.47) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL22503014 | 0.73 | FFAR1 (0.33) | LMNAALDH1A1SMN1; SMN2PKMMAPK1 | |
| SCHEMBL5174689 | 0.73 | ALDH1A1 (0.42) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL6845929 | 0.73 | ALDH1A1 (0.42) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL1453904 | 0.71 | L3MBTL1 (0.45) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL9184304 | 0.71 | HTT (0.49) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL11456052 | 0.71 | L3MBTL1 (0.45) | LMNAALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL95522 | 0.70 | LMNA (0.42) | LMNAALDH1A1L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283689-B | Method for preparing thioester compound by alkene carbonylation thioesterification reaction | 中国科学院兰州化学物理研究所 | 2023-10-31 | — | — | CN | disclosed |
| CN-116283689-A | Method for preparing thioester compound by alkene carbonylation thioesterification reaction | 中国科学院兰州化学物理研究所 | 2023-06-23 | — | — | CN | disclosed |