Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978357 | 0.81 | MAPT (0.44) | GPR119MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL5737167 | 0.78 | MAPT (0.42) | MAPTALDH1A1NPC1TP53TSHR | |
| SCHEMBL8159908 | 0.78 | MAPT (0.51) | GPR119MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL6916052 | 0.77 | RAB9A (0.51) | GPR119MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL4514786 | 0.76 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL6529111 | 0.74 | GPR119 (0.46) | GPR119HPGDSMN1; SMN2 | |
| SCHEMBL21596361 | 0.73 | MAPT (0.48) | MAPTRAB9AALDH1A1NPC1LMNA | |
| SCHEMBL21750394 | 0.72 | MAPT (0.56) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25320235 | 0.71 | HDAC6 (0.55) | MAPTRAB9AALDH1A1NPC1LMNA | |
| SCHEMBL6749864 | 0.71 | GPR119 (0.32) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507607-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2023-07-28 | — | — | CN | disclosed |