Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251866 | 0.88 | PLCG1 (0.56) | PLCG1ATMMMP2HSD17B2L3MBTL1 | |
| SCHEMBL99072 | 0.82 | PSIP1 (0.56) | ATMMMP2HSD17B2EDNRBEDNRA | |
| SCHEMBL265696 | 0.78 | PTGS2 (0.46) | ATMMMP2HSD17B2EDNRBEDNRA | |
| SCHEMBL29595880 | 0.78 | PTGS2 (0.46) | ATMMMP2HSD17B2EDNRBEDNRA | |
| SCHEMBL263686 | 0.78 | ATM (0.46) | ATMMMP2HSD17B2L3MBTL1EDNRB | |
| SCHEMBL6726327 | 0.77 | ATM (0.45) | ATMMMP2HSD17B2L3MBTL1EDNRB | |
| SCHEMBL17364184 | 0.77 | ATM (0.45) | ATMMMP2HSD17B2L3MBTL1PGR | |
| SCHEMBL3600024 | 0.77 | ATM (0.49) | PLCG1ATMMMP2HSD17B2L3MBTL1 | |
| SCHEMBL6544145 | 0.76 | PSIP1 (0.62) | PLCG1ALDH1A1 | |
| SCHEMBL1710715 | 0.75 | ATM (0.41) | ATMMMP2HSD17B2L3MBTL1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |