SCHEMBL265696

SCHEMBL265696

CS(=O)(=O)c1cccc(Br)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C2 P52895 1/20 0.46
HSD17B2 P37059 1/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
EDNRB P24530 2/20 0.44
EDNRA P25101 2/20 0.44
MMP2 P08253 2/20 0.44
PGR P06401 1/20 0.42
MBTD1 Q05BQ5 1/20 0.41
L3MBTL3 Q96JM7 1/20 0.41
BRD4 O60885 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29595880 1.00 PTGS2 (0.46) PTGS2AKR1C3AKR1C2HSD17B2ATM
SCHEMBL1887800 0.83 TAAR1 (0.46) PTGS2AKR1C3AKR1C2ALDH1A1MMP2
SCHEMBL10051059 0.83 CA1 (0.55) ALDH1A1
SCHEMBL18640198 0.83 HSD17B2 (0.43) PTGS2HSD17B2ATMALDH1A1MAPK1
SCHEMBL23913703 0.81 ALDH1A1 (0.48) HSD17B2ATMALDH1A1MAPK1EDNRB
SCHEMBL3679487 0.81 LMNA (0.54) HSD17B2ATMALDH1A1EDNRBEDNRA
SCHEMBL31668877 0.81 LMNA (0.54) HSD17B2ATMALDH1A1EDNRBEDNRA
SCHEMBL31391247 0.81 LMNA (0.54) HSD17B2ATMALDH1A1EDNRBEDNRA
SCHEMBL3035464 0.79 ATM (0.46) HSD17B2ATMALDH1A1MAPK1EDNRB
SCHEMBL99072 0.78 PSIP1 (0.56) HSD17B2ATMALDH1A1MAPK1EDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN claimed
CN-115084655-A Electrolyte, preparation method thereof and lithium metal battery containing electrolyte 蜂巢能源科技(无锡)有限公司 2022-09-20 CN claimed
EP-4743453-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
EP-4685143-A1 DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF Vivozon,Inc. (KR) 2026-01-28 EP disclosed
US-20250382279-A1 COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR Opna Bio SA (CH) 2025-12-18 US disclosed
EP-4654972-A1 COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR Opna Bio SA (CH) 2025-12-03 EP disclosed
US-20250250233-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE PRILENIA NEUROTHERAPEUTICS LTD. (IL) 2025-08-07 US disclosed
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-07-03 US disclosed
US-20250186441-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2025-06-12 US disclosed
EP-4567035-A1 NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Nextgen Bioscience Co., Ltd. (KR) 2025-06-11 EP disclosed
US-20250154109-A1 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE LATIGO BIOTHERAPEUTICS, INC 2025-05-15 US disclosed
US-5696127-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-09 US disclosed
US-5693647-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 US disclosed
US-5693646-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-12-02 US disclosed
US-5688808-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
US-5688810-A Steroid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 1997-11-18 US disclosed
EP-0800519-A1 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 1997-10-15 EP disclosed
WO-1997008145-A1 META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS G.D. SEARLE & CO. (US) 1997-03-06 WO disclosed
WO-1996019458-A2 STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 1996-06-27 WO disclosed
CN-1125221-A 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect GRUENENTHAL GMBH (DE) 1996-06-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154109-A1 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE SCN8A, TRPV1, SCNN1A PTGS2 1147/4885AKR1C3 3612/4885AKR1C2 3734/4885
US-20250250233-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF PRIDOPIDINE QDPR, MAOB, DRD2 PTGS2 1402/4885AKR1C3 2434/4885AKR1C2 1600/4885
US-20250382279-A1 COMPOUNDS AND METHODS FOR YAP/TEAD MODULATION AND INDICATIONS THEREFOR YAP1, YES1, LATS1 PTGS2 2860/4885AKR1C3 2177/4885AKR1C2 1476/4885
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 PTGS2 4496/4885AKR1C3 2119/4885AKR1C2 2268/4885
US-20250186441-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES XDH, PNPO, OAT PTGS2 625/4885AKR1C3 329/4885AKR1C2 282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.