Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079995 | 0.81 | GRIK2 (0.36) | LMNATSHRKMT2AMEN1MAPT | |
| SCHEMBL29822631 | 0.81 | GRIK2 (0.36) | LMNATSHRKMT2AMEN1MAPT | |
| SCHEMBL29822795 | 0.79 | MAPT (0.37) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL29079983 | 0.75 | NPC1 (0.39) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL29080004 | 0.73 | ALDH1A1 (0.39) | LMNAKMT2AMEN1MAPTTDP1 | |
| SCHEMBL29079994 | 0.73 | LMNA (0.43) | LMNAKMT2AMEN1DRD2DRD4 | |
| SCHEMBL29079982 | 0.73 | ACHE (0.39) | LMNAKMT2AMAPTSMN1; SMN2TDP1 | |
| SCHEMBL29079988 | 0.71 | ALDH1A1 (0.41) | TSHRKMT2AMEN1CYP2D6DRD2 | |
| SCHEMBL29080008 | 0.71 | LMNA (0.44) | LMNAKMT2AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4020050 | 0.68 | HTT (0.45) | LMNATSHRKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853664-B | Method for synthesizing alpha, beta-unsaturated cyclohexyl ketone compound under palladium catalysis condition | 河南大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-114853664-A | Method for synthesizing alpha, beta-unsaturated heterocyclic hexyl ketone compound under palladium catalysis condition | 河南大学 | 2022-08-05 | — | — | CN | disclosed |