Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29080903 | 0.86 | NPC1 (0.33) | RIPK1MAPTKMT2A | |
| SCHEMBL27177096 | 0.79 | POLB (0.36) | POLBRIPK1MAPTKMT2A | |
| SCHEMBL29080904 | 0.79 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL18367368 | 0.76 | POLB (0.33) | POLBRIPK1MAPTKMT2A | |
| SCHEMBL29080910 | 0.75 | RIPK1 (0.46) | POLBRIPK1MAPTKMT2A | |
| SCHEMBL29080940 | 0.75 | PKM (0.31) | — | |
| SCHEMBL18366602 | 0.75 | RIPK1 (0.43) | POLBRIPK1MAPTKMT2A | |
| SCHEMBL18372599 | 0.73 | RIPK1 (0.35) | POLBRIPK1 | |
| SCHEMBL18366597 | 0.73 | RIPK1 (0.37) | POLBRIPK1MAPTKMT2A | |
| SCHEMBL18366792 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269221-B | Bicyclic lactams and methods of use thereof | 豪夫迈·罗氏有限公司 | 2023-09-26 | — | — | CN | disclosed |