Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264126 | 0.85 | RAB9A (0.47) | POLBNPC1KMT2AHPGDTSHR | |
| SCHEMBL27851482 | 0.80 | MAPT (0.48) | POLBNPC1ALOX12KMT2ATSHR | |
| SCHEMBL2096497 | 0.76 | TAAR1 (0.45) | LMNA | |
| SCHEMBL30578691 | 0.73 | NPC1 (0.55) | POLBNPC1ALOX12KMT2AHPGD | |
| Ethoxycarbonyl Group SCHEMBL29082342 | 0.71 | KMT2A (0.36) | POLBNPC1ALOX12KMT2AHPGD | |
| SCHEMBL29082341 | 0.71 | ALOX12 (0.48) | POLBNPC1ALOX12KMT2AHPGD | |
| SCHEMBL10364620 | 0.68 | NPC1 (0.54) | POLBNPC1ALOX12KMT2AHPGD | |
| SCHEMBL27720342 | 0.68 | TSHR (0.39) | TSHR | |
| SCHEMBL2792565 | 0.68 | HPGD (0.51) | POLBNPC1ALOX12KMT2AHPGD | |
| SCHEMBL27868449 | 0.68 | ALDH1A1 (0.53) | POLBNPC1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768877-A | ISR inhibitor and preparation method and application thereof | 中国药科大学 | 2023-09-19 | — | — | CN | disclosed |