Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTPRJ | Q12913 | 1/20 | 0.36 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439062 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL27923287 | 0.76 | LMNA (0.47) | COMTALDH1A1CYP1A2HIF1AALOX15 | |
| SCHEMBL11293508 | 0.75 | LMNA (0.46) | COMTALDH1A1CYP1A2HIF1AALOX15 | |
| SCHEMBL27825821 | 0.73 | L3MBTL1 (0.48) | ALDH1A1ALOX15HSD17B10HPGDKDM4E | |
| SCHEMBL23246436 | 0.73 | KDM4E (0.52) | COMTALDH1A1CYP1A2HIF1AALOX15 | |
| SCHEMBL2112972 | 0.72 | COMT (0.49) | COMTALDH1A1CYP1A2HIF1AALOX15 | |
| SCHEMBL29564068 | 0.72 | COMT (0.49) | COMTALDH1A1CYP1A2HIF1AALOX15 | |
| SCHEMBL13921642 | 0.72 | ALDH1A1 (0.46) | COMTALDH1A1CYP1A2HIF1AALOX15 | |
| SCHEMBL8847117 | 0.71 | HSD17B10 (0.31) | ALDH1A1CYP1A2HSD17B10CASP1CASP7 | |
| SCHEMBL5243080 | 0.70 | COMT (0.56) | COMTALDH1A1CYP1A2HIF1AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710169-A | Integrin inhibitors and uses thereof | 普利安特治疗公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116710169-A | Integrin inhibitors and uses thereof | 普利安特治疗公司 | 2023-09-05 | — | — | CN | disclosed |