Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 4/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27690393 | 0.74 | NOTUM (0.41) | L3MBTL1LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6244142 | 0.70 | SIRT6 (0.46) | L3MBTL1LMNAALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL2312739 | 0.69 | ROCK1 (0.51) | L3MBTL1LMNAALDH1A1PNMTADRA2A | |
| SCHEMBL6240237 | 0.69 | ACHE (0.43) | L3MBTL1LMNAALDH1A1SMN1; SMN2SIRT6 | |
| SCHEMBL2105761 | 0.68 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1TSHRTDP1PNMT | |
| SCHEMBL26621424 | 0.68 | ALDH1A1 (0.55) | L3MBTL1LMNAALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL5477312 | 0.68 | LMNA (0.48) | L3MBTL1LMNAALDH1A1TSHRTDP1 | |
| SCHEMBL7996831 | 0.67 | L3MBTL1 (0.66) | L3MBTL1LMNAALDH1A1TSHRTDP1 | |
| SCHEMBL17099539 | 0.67 | HTT (0.42) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL4611589 | 0.67 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1PNMTADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621764-A | Preparation method of 3, 3-dimethyl-6-nitro-1, 3-indoline-2-ketone | 南京合巨药业有限公司 | 2023-08-22 | — | — | CN | disclosed |