Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30603337 | 1.00 | GPR119 (0.41) | GPR119IRAK4MKNK1EGLN2PARP1 | |
| SCHEMBL30603339 | 0.88 | MKNK1 (0.47) | MKNK1PARP1TNKS2PARP2P2RX7 | |
| SCHEMBL29330275 | 0.78 | MKNK1 (0.48) | MKNK1P2RX7 | |
| SCHEMBL29329976 | 0.76 | PARP1 (0.42) | GPR119MKNK1PARP1TNKS2PARP2 | |
| SCHEMBL29330191 | 0.76 | MKNK1 (0.43) | MKNK1PARP1TNKS2PARP2 | |
| SCHEMBL29090285 | 0.75 | DRD2 (0.36) | — | |
| SCHEMBL30603355 | 0.75 | DRD2 (0.36) | — | |
| SCHEMBL29899510 | 0.74 | GPR119 (0.44) | GPR119MKNK1PARP1TNKS2PARP2 | |
| SCHEMBL29899537 | 0.71 | MKNK1 (0.46) | MKNK1PARP1TNKS2PARP2 | |
| SCHEMBL21807381 | 0.71 | TRPC5 (0.58) | MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731013-A | Heterocyclic compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |