Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.46 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.46 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.46 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787970 | 0.83 | PTGDR2 (0.47) | HTR6PTGDR2HTTCACNB4CACNA1A | |
| SCHEMBL5514366 | 0.82 | PTGER3 (0.44) | MAPTPOLBCACNB4CACNA1ACACNA1G | |
| SCHEMBL20787968 | 0.82 | HDAC1 (0.48) | HTR6CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL21295511 | 0.82 | PLA2G2A (0.48) | HTR6ICMTCACNB4CACNA1ACACNA1G | |
| SCHEMBL12225809 | 0.81 | POLB (0.63) | HTTMAPTPTGS2POLBALDH1A1 | |
| SCHEMBL18508845 | 0.81 | ALDH1A1 (0.65) | HTTMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9584802 | 0.81 | ICMT (0.54) | HTR6HTTPTGS2POLBICMT | |
| SCHEMBL7390217 | 0.80 | HDAC1 (0.62) | HTR6PTGS2POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL25322499 | 0.79 | PTGS2 (0.54) | HTR6PTGDR2HTTMAPTPTGS2 | |
| SCHEMBL16494825 | 0.79 | HTR6 (0.64) | HTR6ALDH1A1LMNAKMT2ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924964-A | Preparation method of tetrahydrocarbazole ring compound | 四川轻化工大学 | 2023-10-24 | — | — | CN | claimed |
| CN-116924964-A | Preparation method of tetrahydrocarbazole ring compound | 四川轻化工大学 | 2023-10-24 | — | — | CN | disclosed |