Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094518 | 0.79 | ALOX15 (0.41) | ALOX15HSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL8329202 | 0.76 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL29094466 | 0.75 | ALOX15 (0.37) | ALOX15HSP90AA1HSP90AB1KMT2AMEN1 | |
| SCHEMBL16035268 | 0.72 | LMNA (0.46) | KMT2AALDH1A1PAX8LMNASMN1; SMN2 | |
| SCHEMBL29094509 | 0.68 | ALDH1A1 (0.44) | ALOX15KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL439225 | 0.65 | KDM4E (0.49) | ALOX15KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL3469899 | 0.64 | KDM4E (0.42) | ALOX15KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2117930 | 0.63 | ALDH1A1 (0.41) | ALOX15KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2115936 | 0.63 | ALDH1A1 (0.41) | ALOX15KMT2AMEN1CXCR2KDM4E | |
| SCHEMBL12035536 | 0.63 | ALDH1A1 (0.41) | ALOX15KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685318-A | Heterocyclic compounds and their use for parasitic diseases | 细胞基因公司 | 2023-09-01 | — | — | CN | disclosed |