Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268060 | 0.87 | BCHE (0.41) | NPC1RAB9AFBP1BCHEPOLB | |
| SCHEMBL20562244 | 0.87 | BCHE (0.41) | NPC1RAB9AFBP1BCHEPOLB | |
| SCHEMBL76727 | 0.87 | BCHE (0.41) | NPC1RAB9AFBP1BCHEPOLB | |
| SCHEMBL18308942 | 0.83 | MAPT (0.45) | HTTATML3MBTL1NPC1RAB9A | |
| SCHEMBL29094776 | 0.82 | G6PD (0.51) | L3MBTL1NPC1RAB9ALMNAACHE | |
| SCHEMBL29094816 | 0.82 | G6PD (0.51) | NPC1ACHEBACE1FBP1BCHE | |
| SCHEMBL29094784 | 0.82 | ALDH1A1 (0.56) | NPC1RAB9AACHEBACE1FBP1 | |
| SCHEMBL29094810 | 0.81 | TRPA1 (0.49) | HTTRAB9ALMNAFBP1POLB | |
| SCHEMBL29094804 | 0.81 | FBP1 (0.45) | ATMNPC1RAB9AACHEBACE1 | |
| SCHEMBL29094778 | 0.81 | RAB9A (0.43) | HTTL3MBTL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583970-B | Method for preparing alpha- (hydroxyamino) diaryl phosphine oxide from nitrone | 华北理工大学 | 2024-11-26 | — | — | CN | disclosed |
| CN-115583970-A | Method for preparing alpha- (hydroxy amino) diaryl phosphine oxide from nitrone | 华北理工大学 | 2023-01-10 | — | — | CN | disclosed |