Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271967 | 0.89 | P2RX7 (0.35) | P2RX7PTGDR2POLBL3MBTL1CD38 | |
| SCHEMBL271519 | 0.81 | ALDH1A1 (0.36) | TDP1L3MBTL1 | |
| SCHEMBL271665 | 0.79 | P2RX7 (0.33) | P2RX7POLBCD38 | |
| SCHEMBL271332 | 0.78 | ATM (0.38) | PTGDR2POLB | |
| SCHEMBL271183 | 0.78 | POLB (0.33) | POLBL3MBTL1 | |
| SCHEMBL271417 | 0.70 | ALDH1A1 (0.39) | PTGDR2POLBTDP1L3MBTL1 | |
| SCHEMBL271319 | 0.69 | POLB (0.35) | P2RX7POLB | |
| SCHEMBL271718 | 0.68 | RORC (0.33) | P2RX7PTGDR2POLB | |
| SCHEMBL271924 | 0.68 | POLB (0.32) | POLB | |
| SCHEMBL271950 | 0.68 | ACLY (0.35) | P2RX7PTGDR2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063180-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |