Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 1.00 |
| ▸ | CHRNB4 | P30926 | 1/20 | 1.00 |
| ▸ | CHRNA3 | P32297 | 1/20 | 1.00 |
| ▸ | CHRNA7 | P36544 | 1/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abt-418 SCHEMBL8114587 | 1.00 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Abt-418 SCHEMBL194161 | 1.00 | CHRNB2 (1.00) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Abt-418 SCHEMBL8106821 | 0.98 | CHRNB2 (0.97) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Abt-418 SCHEMBL7586948 | 0.98 | CHRNB2 (0.97) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Abt-418 SCHEMBL7130413 | 0.98 | CHRNB2 (0.97) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9263504 | 0.95 | CHRNB2 (0.91) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL9260223 | 0.94 | CHRNB2 (0.88) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Abt-418 SCHEMBL8114179 | 0.93 | CHRNB2 (0.86) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL14112932 | 0.90 | CHRNB2 (0.81) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL9270411 | 0.88 | CHRNB2 (0.79) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102014995-A | Device and method for delivering a medicament | UNIV DUKE | 2011-04-13 | — | — | CN | claimed |
| EP-2134395-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | Duke University (US) | 2009-12-23 | — | — | EP | claimed |
| WO-2008121610-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | DUKE UNIVERSITY (US) | 2008-10-09 | — | — | WO | claimed |
| US-20080241255-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | DUKE UNIVERSITY (US) | 2008-10-02 | — | — | US | claimed |
| EP-0802790-B1 | TRANSDERMAL THERAPEUTIC SYSTEM FOR DISPENSING (S)-3-METHYL-5-(1-METHYL-2-PYRROLIDENYL)-ISOXAZOLE OR ONE OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS | ABBOTT LAB (US) | 2005-04-06 | — | — | EP | claimed |
| CN-1081459-C | transdermal drug delivery device | MINNESODA MINING AND MFG CO (US) | 2002-03-27 | — | — | CN | claimed |
| EP-0818994-B1 | METHOD OF MAKING A PRESSURE SENSITIVE SKIN ADHESIVE SHEET MATERIAL | MINNESOTA MINING & MFG (US) | 2001-10-24 | — | — | EP | claimed |
| EP-0732922-B1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING & MFG (US) | 2001-03-28 | — | — | EP | claimed |
| EP-0818994-A1 | METHOD OF MAKING A PRESSURE SENSITIVE SKIN ADHESIVE SHEET MATERIAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-21 | — | — | EP | claimed |
| US-5688523-A | Method of making a pressure sensitive skin adhesive sheet material | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-11-18 | — | — | US | claimed |
| US-5585111-A | BACKING BEARING ADHESIVE LAYER COMPRISING HOMOGENEOUS MIXTURE OF COPOLYMER CONTAINING ALKYL ACRYLATE OR METHACRYLATE, /S/-3-METHYL-5-/1-METHYL-2-PYRROLIDINYL/ISOXAZOLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-17 | — | — | US | claimed |
| CN-1136773-A | transdermal drug delivery device | MINNESODA MINING AND MANUFACTU (US) | 1996-11-27 | — | — | CN | claimed |
| WO-1996030001-A1 | METHOD OF MAKING A PRESSURE SENSITIVE SKIN ADHESIVE SHEET MATERIAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-10-03 | — | — | WO | claimed |
| EP-0732922-A1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-25 | — | — | EP | claimed |
| EP-0717741-A1 | METHOD OF PREPARING ENANTIOMERICALLY-PURE 3-METHYL-5-(1-ALKYL-2(S)-PYRROLIDINYL)ISOXAZOLES | ABBOTT LABORATORIES (US) | 1996-06-26 | — | — | EP | claimed |
| US-5516912-A | FROM PROTECTED 2-OXOPYRROLIDINE | ABBOTT LABORATORIES (US) | 1996-05-14 | — | — | US | claimed |
| US-5494680-A | Transdermal delivery device | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-27 | — | — | US | claimed |
| WO-1995015754-A1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-15 | — | — | WO | claimed |
| WO-1995007277-A1 | METHOD OF PREPARING ENANTIOMERICALLY-PURE 3-METHYL-5-(1-ALKYL-2(S)-PYRROLIDINYL)ISOXAZOLES | ABBOTT LABORATORIES (US) | 1995-03-16 | — | — | WO | claimed |
| CN-112656038-B | Resealable aerosol-generating article | 菲利普莫里斯生产公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112716051-B | Aerosol generating system comprising a ruptured portion | 菲利普莫里斯生产公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11805809-B2 | Aerosol-generating system comprising a rupturing portion | PHILIP MORRIS PRODUCTS S.A. (CH) | 2023-11-07 | — | — | US | disclosed |
| US-20220218874-A1 | COMPOSITIONS AND METHODS OF MODULATING ENDOCHONDRAL OSSIFICATION AND BONE FORMATION | UNIV CASE WESTERN RESERVE (US) | 2022-07-14 | — | — | US | disclosed |
| CN-114732167-A | Aerosol-generating system comprising an integrated piercing element | 菲利普莫里斯生产公司 | 2022-07-12 | — | — | CN | disclosed |
| US-11246998-B2 | Aerosol-generating system with differential heating | PHILIP MORRIS PRODUCTS S.A. (CH) | 2022-02-15 | — | — | US | disclosed |
| CN-107404950-B | Aerosol-generating system comprising an integrated piercing element | 菲利普莫里斯生产公司 | 2022-02-08 | — | — | CN | disclosed |
| US-20210219614-A1 | AEROSOL-GENERATING SYSTEM COMPRISING INTEGRATED PIERCING ELEMENT | PHILIP MORRIS PRODUCTS S.A. (CH) | 2021-07-22 | — | — | US | disclosed |
| US-11013872-B2 | Aerosol-generating system for generating and controlling the quantity of nicotine salt particles | PHILIP MORRIS PRODUCTS S.A. (CH) | 2021-05-25 | — | — | US | disclosed |
| US-10994085-B2 | Aerosol-generating system comprising integrated piercing element | PHILIP MORRIS PRODUCTS S.A. (CH) | 2021-05-04 | — | — | US | disclosed |
| CN-112716051-A | Aerosol-generating system comprising a rupturing portion | 菲利普莫里斯生产公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-112656038-A | Resealable aerosol-generating article | 菲利普莫里斯生产公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-107405462-B | Aerosol-generating system comprising a rupturing portion | 菲利普莫里斯生产公司 | 2021-03-23 | — | — | CN | disclosed |
| US-20210052834-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A RUPTURING PORTION | PHILIP MORRIS PRODUCTS S.A. (CH) | 2021-02-25 | — | — | US | disclosed |
| CN-107427077-B | Resealable aerosol-generating article | 菲利普莫里斯生产公司 | 2021-02-02 | — | — | CN | disclosed |
| US-10806873-B2 | Aerosol-generating system comprising a resilient member | PHILIP MORRIS PRODUCTS S.A. (CH) | 2020-10-20 | — | — | US | disclosed |
| CN-107427081-B | Aerosol-generating system comprising a resilient component | 菲利普莫里斯生产公司 | 2020-10-16 | — | — | CN | disclosed |
| US-10786007-B2 | Resealable aerosol-generating article | PHILIP MORRIS PRODUCTS S.A. (CH) | 2020-09-29 | — | — | US | disclosed |
| US-10750785-B2 | Aerosol-generating system comprising a bimetallic strip | PHILIP MORRIS PRODUCTS S.A. (CH) | 2020-08-25 | — | — | US | disclosed |
| EP-2477607-B1 | IMPROVED DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | PHILIP MORRIS PRODUCTS SA (CH) | 2020-08-05 | — | — | EP | disclosed |
| US-10721963-B2 | Electrically heated aerosol delivery system | PHILIP MORRIS PRODUCTS S.A. (CH) | 2020-07-28 | — | — | US | disclosed |
| US-10668058-B2 | Device and method for delivery of a medicament | PHILIP MORRIS PRODUCTS S.A. (CH) | 2020-06-02 | — | — | US | disclosed |
| EP-2134395-B1 | DEVICE FOR DELIVERY OF A MEDICAMENT | PHILIP MORRIS PRODUCTS SA (CH) | 2020-03-18 | — | — | EP | disclosed |
| EP-3551199-A1 | COMPOSITIONS AND METHODS OF MODULATING ENDOCHONDRAL OSSIFICATION AND BONE FORMATION | Case Western Reserve University (US) | 2019-10-16 | — | — | EP | disclosed |
| US-20180303818-A1 | COMPOSITIONS COMPRISING NICOTINIC AGONISTS AND METHODS OF USING SAME | NEURODERM LTD (IL) | 2018-10-25 | — | — | US | disclosed |
| WO-2018107157-A1 | COMPOSITIONS AND METHODS OF MODULATING ENDOCHONDRAL OSSIFICATION AND BONE FORMATION | CASE WESTERN RESERVE UNIVERISTY (US) | 2018-06-14 | — | — | WO | disclosed |
| US-9974743-B2 | Device and method for delivery of a medicament | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-05-22 | — | — | US | disclosed |
| US-20180104425-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A RESILIENT MEMBER | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-04-19 | — | — | US | disclosed |
| US-20180043113-A1 | AEROSOL-GENERATING SYSTEM COMPRISING INTEGRATED PIERCING ELEMENT | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-02-15 | — | — | US | disclosed |
| US-20180042304-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A BIMETALLIC STRIP | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-02-15 | — | — | US | disclosed |
| US-20180042305-A1 | RESEALABLE AEROSOL-GENERATING ARTICLE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2018-02-15 | — | — | US | disclosed |
| EP-3273812-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A RUPTURING PORTION | Philip Morris Products S.a.s. (CH) | 2018-01-31 | — | — | EP | disclosed |
| EP-3273813-A1 | RESEALABLE AEROSOL-GENERATING ARTICLE | Philip Morris Products S.a.s. (CH) | 2018-01-31 | — | — | EP | disclosed |
| EP-3273811-A1 | AEROSOL-GENERATING SYSTEM COMPRISING INTEGRATED PIERCING ELEMENT | Philip Morris Products S.a.s. (CH) | 2018-01-31 | — | — | EP | disclosed |
| EP-3273815-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A BIMETALLIC STRIP | Philip Morris Products S.a.s. (CH) | 2018-01-31 | — | — | EP | disclosed |
| EP-3273814-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A RESILIENT MEMBER | Philip Morris Products S.a.s. (CH) | 2018-01-31 | — | — | EP | disclosed |
| EP-2967138-B1 | AEROSOL-GENERATING SYSTEM WITH DIFFERENTIAL HEATING | PHILIP MORRIS PRODUCTS SA (CH) | 2017-11-22 | — | — | EP | disclosed |
| US-20170128432-A1 | COMPOSITIONS COMPRISING NICOTINIC AGONISTS AND METHODS OF USING SAME | NEURODERM, LTD. (IL) | 2017-05-11 | — | — | US | disclosed |
| CN-103418062-B | Device and method for delivery of a medicament | 菲利普莫里斯生产公司 | 2017-04-12 | — | — | CN | disclosed |
| US-20160309784-A1 | AEROSOL-GENERATING SYSTEM FOR GENERATING AND CONTROLLING THE QUANTITY OF NICOTINE SALT PARTICLES | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-10-27 | — | — | US | disclosed |
| EP-3082484-A1 | AEROSOL-GENERATING SYSTEM FOR GENERATING AND CONTROLLING THE QUANTITY OF NICOTINE SALT PARTICLES | Philip Morris Products S.A. (CH) | 2016-10-26 | — | — | EP | disclosed |
| WO-2016156217-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A RESILIENT MEMBER | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016156216-A1 | RESEALABLE AEROSOL-GENERATING ARTICLE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016156213-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A BIMETALLIC STRIP | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016156212-A1 | AEROSOL-GENERATING SYSTEM COMPRISING INTEGRATED PIERCING ELEMENT | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-10-06 | — | — | WO | disclosed |
| WO-2016156214-A1 | AEROSOL-GENERATING SYSTEM COMPRISING A RUPTURING PORTION | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-10-06 | — | — | WO | disclosed |
| US-20160250201-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | PHILIP MORRIS PRODUCTS SA (CH) | 2016-09-01 | — | — | US | disclosed |
| CN-105792688-A | Aerosol-generating system for generating and controlling the quantity of nicotine salt particles | 菲利普莫里斯生产公司 | 2016-07-20 | — | — | CN | disclosed |
| EP-2999507-A1 | AEROSOL COMPRISING DISTRIBUTING AGENT AND A MEDICAMENT SOURCE | Philip Morris Products S.A. (CH) | 2016-03-30 | — | — | EP | disclosed |
| EP-2999365-A2 | ELECTRICALLY HEATED AEROSOL DELIVERY SYSTEM | Philip Morris Products S.A. (CH) | 2016-03-30 | — | — | EP | disclosed |
| US-20160081395-A1 | ELECTRICALLY HEATED AEROSOL DELIVERY SYSTEM | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-03-24 | — | — | US | disclosed |
| CN-105407748-A | Electrically heated aerosol delivery system | PHILIP MORRIS PRODUCTS SA | 2016-03-16 | — | — | CN | disclosed |
| US-20160022930-A1 | AEROSOL-GENERATING SYSTEM WITH DIFFERENTIAL HEATING | PHILIP MORRIS PRODUCTS S.A. (CH) | 2016-01-28 | — | — | US | disclosed |
| EP-2967138-A1 | AEROSOL-GENERATING SYSTEM WITH DIFFERENTIAL HEATING | Philip Morris Products S.A. (CH) | 2016-01-20 | — | — | EP | disclosed |
| CN-105188817-A | Aerosol comprising distributing agent and a medicament source | PHILIP MORRIS PRODUCTS SA | 2015-12-23 | — | — | CN | disclosed |
| US-20150306109-A1 | Compositions Comprising Nicotinic Agonists and Methods of Using Same | NEURODERM, LTD. (IL) | 2015-10-29 | — | — | US | disclosed |
| US-9169240-B2 | Ketone linked benzothiazole inhibitors of endothelial lipase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| CN-104994757-A | Aerosol-generating system utilizing differential heating | PHILIP MORRIS PRODUCTS SA | 2015-10-21 | — | — | CN | disclosed |
| CN-104906669-A | Device and method for delivery of a medicament | UNIV DUKE | 2015-09-16 | — | — | CN | disclosed |
| US-20150239879-A1 | KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY | 2015-08-27 | — | — | US | disclosed |
| WO-2015091258-A1 | AEROSOL-GENERATING SYSTEM FOR GENERATING AND CONTROLLING THE QUANTITY OF NICOTINE SALT PARTICLES | PHILIP MORRIS PRODUCTS S.A. (CH) | 2015-06-25 | — | — | WO | disclosed |
| CN-102014995-B | Device and method for delivering a medicament | PHILIP MORRIS PRODUCTS SA | 2015-05-13 | — | — | CN | disclosed |
| US-8921356-B2 | Compositions comprising nicotinic agonists and methods of using same | NEURODERM, LTD. (IL) | 2014-12-30 | — | — | US | disclosed |
| WO-2014187763-A1 | AEROSOL COMPRISING DISTRIBUTING AGENT AND A MEDICAMENT SOURCE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2014-11-27 | — | — | WO | disclosed |
| WO-2014187770-A2 | ELECTRICALLY HEATED AEROSOL DELIVERY SYSTEM | PHILIP MORRIS PRODUCTS S.A. (CH) | 2014-11-27 | — | — | WO | disclosed |
| WO-2014140320-A1 | AEROSOL-GENERATING SYSTEM WITH DIFFERENTIAL HEATING | PHILIP MORRIS PRODUCTS S.A. (CH) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014042939-A1 | KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-03-20 | — | — | WO | disclosed |
| EP-2708256-A2 | Device and method for delivery of a medicament | Philip Morris Products S.A. (CH) | 2014-03-19 | — | — | EP | disclosed |
| CN-103418062-A | Device and method for delivery of a medicament | PHILIP MORRIS PRODUCTS SA | 2013-12-04 | — | — | CN | disclosed |
| US-20130172321-A1 | Compositions Comprising Nicotinic Agonists and Methods of Using Same | NEURODERM, LTD. (IL) | 2013-07-04 | — | — | US | disclosed |
| EP-2559427-A1 | Transdermal therapeutic system having a content of a modulator for nicotinic acetylcholine receptors (nAChR) | Acino AG (DE) | 2013-02-20 | — | — | EP | disclosed |
| EP-2217206-B1 | TRANSDERMAL THERAPEUTIC SYSTEM HAVING A CONTENT OF A MODULATOR FOR NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR) | ACINO AG (DE) | 2012-10-24 | — | — | EP | disclosed |
| US-20120255567-A1 | IMPROVED DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | PHILIP MORRIS PRODUCTS S.A. (CH) | 2012-10-11 | — | — | US | disclosed |
| US-8273731-B2 | Compositions comprising nicotinic agonists and methods of using same | NEURODERM LTD. (IL) | 2012-09-25 | — | — | US | disclosed |
| CN-102612361-A | Improved device and method for delivering medication | UNIV DUKE | 2012-07-25 | — | — | CN | disclosed |
| EP-2224917-A1 | COMPOSITIONS COMPRISING NICOTINIC AGONISTS AND METHODS OF USING SAME | Neuroderm Ltd (IL) | 2010-09-08 | — | — | EP | disclosed |
| EP-2217206-A2 | TRANSDERMAL THERAPEUTIC SYSTEM HAVING A CONTENT OF A MODULATOR FOR NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR) | Acino AG (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090149446-A1 | Compositions Comprising Nicotinic Agonists and Methods of Using Same | NEURODERM, LTD. | 2009-06-11 | — | — | US | disclosed |
| WO-2009071326-A2 | TRANSDERMAL THERAPEUTIC SYSTEM HAVING A CONTENT OF A MODULATOR FOR NICOTINIC ACETYLCHOLINE RECEPTORS (NACHR) | ACINO AG (DE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009069126-A1 | COMPOSITIONS COMPRISING NICOTINIC AGONISTS AND METHODS OF USING SAME | NEURODERM LTD (IL) | 2009-06-04 | — | — | WO | disclosed |
| US-20090068642-A1 | Composition and pharmacology of novel alpha6-containing nicotinic acetylcholine receptors | TARGACEPT, INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2008122049-A2 | METHODS AND COMPOSITIONS FOR REDUCTION OF SIDE EFFECTS OF THERAPEUTIC TREATMENTS | PARKINSON'S INSTITUTE (US) | 2008-10-09 | — | — | WO | disclosed |
| US-20080241255-A1 | DEVICE AND METHOD FOR DELIVERY OF A MEDICAMENT | DUKE UNIVERSITY (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080167297-A1 | Pyrimidine Derivatives for Use as Anticancer Agents | ASTRAZENECA AB (SE) | 2008-07-10 | — | — | US | disclosed |
| US-20080161330-A1 | Pyrimidines as Igf-I Inhibitors | ASTRAZENECA AB (SE) | 2008-07-03 | — | — | US | disclosed |
| WO-2005030145-A2 | COMPOSITION AND PHARMACOLOGY OF NOVEL ALPHA-6-CONTAINING NICOTINIC ACETYLCHOLINE RECEPTORS | TARGACEPT, INC. (US) | 2005-04-07 | — | — | WO | disclosed |
| EP-0802790-B1 | TRANSDERMAL THERAPEUTIC SYSTEM FOR DISPENSING (S)-3-METHYL-5-(1-METHYL-2-PYRROLIDENYL)-ISOXAZOLE OR ONE OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS | ABBOTT LAB (US) | 2005-04-06 | — | — | EP | disclosed |
| CN-1081459-C | transdermal drug delivery device | MINNESODA MINING AND MFG CO (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1081459-C | transdermal drug delivery device | MINNESODA MINING AND MFG CO (US) | 2002-03-27 | — | — | CN | disclosed |
| EP-0818994-B1 | METHOD OF MAKING A PRESSURE SENSITIVE SKIN ADHESIVE SHEET MATERIAL | MINNESOTA MINING & MFG (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-1126846-A1 | USE OF A NICOTINE RECEPTOR AGONIST IN THE TREATMENT OF OBSESSIVE COMPULSIVE DISORDER | A Carlsson Research AB (SE) | 2001-08-29 | — | — | EP | disclosed |
| EP-0717741-B1 | METHOD OF PREPARING ENANTIOMERICALLY-PURE 3-METHYL-5-(1-ALKYL-2(S)-PYRROLIDINYL)ISOXAZOLES | ABBOTT LAB (US) | 2001-05-30 | — | — | EP | disclosed |
| EP-0732922-B1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING & MFG (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-0732922-B1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING & MFG (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-0588917-B1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LAB (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000025783-A1 | USE OF A NICOTINE RECEPTOR AGONIST IN THE TREATMENT OF OBSESSIVE COMPULSIVE DISORDER | A CARLSSON RESEARCH AB (SE) | 2000-05-11 | — | — | WO | disclosed |
| US-6041789-A | Cigarette substitute device and composition for use therein | K&B TECHNOLOGIES, L.L.C. (US) | 2000-03-28 | — | — | US | disclosed |
| EP-0981539-A1 | DOLASTATIN 15 DERIVATIVES WITH CARBONYL AND HETEROCYCLIC FUNCTIONALITIES AT THE C-TERMINUS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-01 | — | — | EP | disclosed |
| US-5965537-A | ANTICANCER AGENTS; WATER SOLUBILITY | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-12 | — | — | US | disclosed |
| WO-1998040400-A1 | DOLASTATIN 15 DERIVATIVES WITH CARBONYL AND HETEROCYCLIC FUNCTIONALITIES AT THE C-TERMINUS | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |
| EP-0818994-A1 | METHOD OF MAKING A PRESSURE SENSITIVE SKIN ADHESIVE SHEET MATERIAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5688523-A | Method of making a pressure sensitive skin adhesive sheet material | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-11-18 | — | — | US | disclosed |
| US-5585111-A | BACKING BEARING ADHESIVE LAYER COMPRISING HOMOGENEOUS MIXTURE OF COPOLYMER CONTAINING ALKYL ACRYLATE OR METHACRYLATE, /S/-3-METHYL-5-/1-METHYL-2-PYRROLIDINYL/ISOXAZOLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5585111-A | BACKING BEARING ADHESIVE LAYER COMPRISING HOMOGENEOUS MIXTURE OF COPOLYMER CONTAINING ALKYL ACRYLATE OR METHACRYLATE, /S/-3-METHYL-5-/1-METHYL-2-PYRROLIDINYL/ISOXAZOLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| CN-1136773-A | transdermal drug delivery device | MINNESODA MINING AND MANUFACTU (US) | 1996-11-27 | — | — | CN | disclosed |
| CN-1136773-A | transdermal drug delivery device | MINNESODA MINING AND MANUFACTU (US) | 1996-11-27 | — | — | CN | disclosed |
| WO-1996030001-A1 | METHOD OF MAKING A PRESSURE SENSITIVE SKIN ADHESIVE SHEET MATERIAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-10-03 | — | — | WO | disclosed |
| EP-0732922-A1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0732922-A1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| US-5559242-A | FROM PYROGLUTAMIC ACID, ESTERIFICATION, REACTION WITH DIANION OF ACETONE OXIME, CYCLIZATION, REDUCTION, ALKYLATION | ABBOTT LABORATORIES (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0717741-A1 | METHOD OF PREPARING ENANTIOMERICALLY-PURE 3-METHYL-5-(1-ALKYL-2(S)-PYRROLIDINYL)ISOXAZOLES | ABBOTT LABORATORIES (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5516912-A | FROM PROTECTED 2-OXOPYRROLIDINE | ABBOTT LABORATORIES (US) | 1996-05-14 | — | — | US | disclosed |
| US-5508418-A | FOR MAKING CHOLINERGIC OR ANXIOLYTIC AGENTS | ABBOTT LABORATORIES (US) | 1996-04-16 | — | — | US | disclosed |
| US-5494680-A | Transdermal delivery device | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| US-5494680-A | Transdermal delivery device | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1995015754-A1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-15 | — | — | WO | disclosed |
| WO-1995015754-A1 | TRANSDERMAL DELIVERY DEVICE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-06-15 | — | — | WO | disclosed |
| US-5424444-A | Reacting N-alkyl-L-proline ester with salt of dianion of acetone oxime or acetonitrile or other imine anion compounds; cyclization, dehydration after reaction with Grignard reagent and hydroxylamine | ABBOTT LABORATORIES (US) | 1995-06-13 | — | — | US | disclosed |
| US-5409946-A | Antiepileptic agent | ABBOTT LABORATORIES (US) | 1995-04-25 | — | — | US | disclosed |
| WO-1995007277-A1 | METHOD OF PREPARING ENANTIOMERICALLY-PURE 3-METHYL-5-(1-ALKYL-2(S)-PYRROLIDINYL)ISOXAZOLES | ABBOTT LABORATORIES (US) | 1995-03-16 | — | — | WO | disclosed |
| EP-0588917-A4 | — | — | 1994-04-13 | — | — | EP | disclosed |
| EP-0588917-A1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LABORATORIES (US) | 1994-03-30 | — | — | EP | disclosed |
| WO-1992021339-A1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1992021339-A1 | ISOXAZOLE AND ISOTHIAZOLE COMPOUNDS THAT ENHANCE COGNITIVE FUNCTION | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167297-A1 | Pyrimidine Derivatives for Use as Anticancer Agents | IGF1R, TYMP, IGFBP1 | CHRNB2 4819/4885CHRNB4 4840/4885CHRNA3 4704/4885 |
| US-20080161330-A1 | Pyrimidines as Igf-I Inhibitors | IGF1R, IGFBP1, IGFBP2 | CHRNB2 4427/4885CHRNB4 4595/4885CHRNA3 3894/4885 |
| US-20150239879-A1 | KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | LIPG, LPL, LIPE | CHRNB2 4483/4885CHRNB4 4357/4885CHRNA3 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.