Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 7/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 7/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP14 | P50281 | 3/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117249 | 1.00 | MMP3 (0.48) | MMP3MMP2LMNAMMP1MMP9 | |
| SCHEMBL29178370 | 0.88 | CALM1 (0.39) | MMP3MMP2LMNAPPARGPPARA | |
| SCHEMBL29178372 | 0.88 | CALM1 (0.39) | MMP3MMP2LMNAPPARGPPARA | |
| SCHEMBL29178416 | 0.86 | MMP2 (0.39) | MMP3MMP2LMNAKMT2A | |
| SCHEMBL29178413 | 0.86 | MMP2 (0.39) | MMP3MMP2LMNAKMT2A | |
| SCHEMBL29178307 | 0.85 | CHRNA7 (0.46) | KMT2A | |
| SCHEMBL29178311 | 0.85 | CHRNA7 (0.46) | KMT2A | |
| SCHEMBL29178414 | 0.83 | HDAC1 (0.44) | MMP3MMP2PPARAKMT2A | |
| SCHEMBL29178315 | 0.83 | MPO (0.38) | MMP3MMP2 | |
| SCHEMBL28562272 | 0.82 | SRR (0.50) | MMP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117177744-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2023-12-05 | — | — | CN | disclosed |