Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.45 |
| ▸ | PTAFR | P25105 | 4/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178311 | 1.00 | CHRNA7 (0.46) | CHRNA7TBXAS1PTAFRCYP2A6RECQL | |
| SCHEMBL29178416 | 0.85 | MMP2 (0.39) | HRH1KMT2A | |
| SCHEMBL29178413 | 0.85 | MMP2 (0.39) | HRH1KMT2A | |
| SCHEMBL29117246 | 0.85 | MMP3 (0.48) | KMT2A | |
| SCHEMBL29117249 | 0.85 | MMP3 (0.48) | KMT2A | |
| SCHEMBL29178466 | 0.84 | CHRNA7 (0.45) | CHRNA7TBXAS1PTAFRTDP1L3MBTL1 | |
| SCHEMBL24814131 | 0.81 | TBXAS1 (0.50) | CHRNA7TBXAS1PTAFRCYP2A6RECQL | |
| SCHEMBL29178370 | 0.79 | CALM1 (0.39) | TBXAS1 | |
| SCHEMBL29178372 | 0.79 | CALM1 (0.39) | TBXAS1 | |
| SCHEMBL29178353 | 0.77 | LMNA (0.42) | TDP1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |