Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2687037 | 0.82 | SLC40A1 (0.39) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL29912312 | 0.82 | SLC40A1 (0.39) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL27854216 | 0.79 | LMNA (0.43) | BLMTDP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL17045827 | 0.74 | S100A4 (0.44) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL14840705 | 0.74 | ERN1 (0.45) | KMT2AERN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL27269490 | 0.72 | TRPV1 (0.40) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL31091927 | 0.72 | PTGS1 (0.34) | MEN1KMT2ATDP1LMNAKDM4E | |
| SCHEMBL31091965 | 0.72 | MEN1 (0.36) | MEN1KMT2AKDM4E | |
| SCHEMBL15624391 | 0.72 | TDP1 (0.44) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL95708 | 0.72 | ERN1 (0.50) | CES1MEN1THRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981670-A | Polycyclic compound containing nitrogen heterocycle, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022194122-A1 | NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2022-09-22 | — | — | WO | disclosed |