Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985838 | 0.93 | LPAR3 (0.32) | LPAR3LPAR2TRPM8 | |
| Zinc Ion SCHEMBL29120166 | 0.93 | LPAR3 (0.32) | LPAR3LPAR2TRPM8 | |
| SCHEMBL29120170 | 0.93 | LPAR3 (0.32) | LPAR3LPAR2TRPM8 | |
| SCHEMBL18378220 | 0.93 | MMP1 (0.33) | LPAR3LPAR2TRPM8 | |
| SCHEMBL17941190 | 0.93 | LPAR3 (0.32) | LPAR3LPAR2TRPM8 | |
| Potassium Ion SCHEMBL29120187 | 0.93 | SLC34A1 (0.33) | LPAR3LPAR2TRPM8 | |
| SCHEMBL18378035 | 0.93 | LPAR3 (0.32) | LPAR3LPAR2TRPM8 | |
| SCHEMBL28343150 | 0.83 | TRPM8 (0.39) | LPAR3LPAR2TRPM8 | |
| SCHEMBL8405559 | 0.81 | L3MBTL1 (0.31) | — | |
| SCHEMBL28900922 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164623-A | Synthesis method of dialkyl phosphinate | 江苏利思德新材料股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-117164623-A | Synthesis method of dialkyl phosphinate | 江苏利思德新材料股份有限公司 | 2023-12-05 | — | — | CN | disclosed |