Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584535 | 0.83 | CYP1A2 (0.78) | CYP1A2MAOBNFKB1TSHRKMT2A | |
| SCHEMBL31414540 | 0.83 | SMN1; SMN2 (0.54) | NFKB1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL24227389 | 0.82 | RAB9A (0.69) | CYP1A2MAOBNFKB1TSHRKMT2A | |
| SCHEMBL8007465 | 0.82 | LMNA (0.60) | KMT2ANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL29122556 | 0.80 | EPHX2 (0.50) | ALDH1A1MCHR1CD274 | |
| SCHEMBL4347910 | 0.79 | SMN1; SMN2 (0.44) | CYP1A2MAOBNFKB1TSHRKMT2A | |
| SCHEMBL29122533 | 0.79 | PKM (0.72) | NFKB1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11476769 | 0.78 | CYP1A2 (0.70) | CYP1A2MAOBNFKB1TSHRKMT2A | |
| SCHEMBL9491749 | 0.78 | HDAC3 (0.76) | CYP1A2MAOBNFKB1TSHRKMT2A | |
| SCHEMBL9585652 | 0.78 | CYP1A2 (0.70) | CYP1A2MAOBNFKB1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117185952-A | Alpha-arylamine compound and preparation method and application thereof | 天津师范大学 | 2023-12-08 | — | — | CN | disclosed |