Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267580 | 0.89 | NPC1 (0.60) | LMNAHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3185081 | 0.85 | SMN1; SMN2 (0.51) | LMNAHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL12833023 | 0.84 | SMN1; SMN2 (0.73) | LMNAHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28007671 | 0.83 | LMNA (0.62) | LMNAHPGDGAASMN1; SMN2POLB | |
| SCHEMBL29123079 | 0.82 | CYP1A2 (0.62) | LMNAALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL4347910 | 0.82 | SMN1; SMN2 (0.44) | LMNAHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL31414540 | 0.82 | SMN1; SMN2 (0.54) | LMNAHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3192014 | 0.82 | LMNA (0.77) | LMNAHPGDGAASMN1; SMN2POLB | |
| SCHEMBL9191272 | 0.81 | LMNA (0.61) | LMNAHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL83922 | 0.81 | HPGD (0.86) | LMNAHPGDALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930488-A | Alkyl trifluoromethyl thioether compound and synthesis method thereof | 常州大学 | 2025-05-06 | — | — | CN | disclosed |
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-06-27 | — | — | US | disclosed |
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2024-06-27 | — | — | US | disclosed |
| WO-2023154291-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| CN-1318054-A | Novel compounds | ASTRA PHARMA PROD (SE) | 2001-10-17 | — | — | CN | disclosed |
| EP-1042274-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000023418-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-04-27 | — | — | WO | disclosed |
| US-4348427-A | Coating method and composition | ANIC, S.P.A. (IT) | 1982-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208922-A1 | A TRIFLUOROMETHYL THIANTHRENIUM COMPOUND, PROCESS FOR PREPARING THE SAME AND THE USE THEREOF | CYP4F3, GTF3C3, GTF3C4 | LMNA 2866/4885HPGD 4385/4885ALDH1A1 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.