Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL29130245 | 0.87 | ALDH1A1 (0.37) | THRBLMNACYP2D6CYP2C9TSHR | |
| Tetrabuthylammonium SCHEMBL9234630 | 0.82 | KCNH2 (0.44) | TDP1LMNACYP2D6CYP2C9TSHR | |
| Tetrabuthylammonium SCHEMBL29130219 | 0.81 | PTGS2 (0.49) | LMNACYP2D6CYP2C9TSHRCYP2C19 | |
| Tetrabuthylammonium SCHEMBL7765608 | 0.81 | TDP1 (0.64) | TDP1LMNACYP2D6CYP2C9TSHR | |
| Tetrabuthylammonium SCHEMBL29130260 | 0.80 | L3MBTL1 (0.36) | TDP1THRBLMNACYP2D6CYP2C9 | |
| Tetrabuthylammonium SCHEMBL28735164 | 0.80 | SLC22A1 (0.52) | TSHRHIF1ATAS1R3TAS1R1CA2 | |
| SCHEMBL26185772 | 0.78 | TAS1R3 (0.35) | TDP1LMNACYP2D6CYP2C9TSHR | |
| SCHEMBL1629035 | 0.76 | CHRNA7 (0.42) | THRBHTTKCNH2TAS1R3TAS1R1 | |
| SCHEMBL26573878 | 0.76 | TAS1R3 (0.38) | TDP1THRBTAS1R3TAS1R1CA2 | |
| SCHEMBL26460127 | 0.75 | PSMD14 (0.43) | TSHRHTTKCNH2HIF1ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164505-A | Method for synthesizing organic sulfate by dialkyl sulfate or pyrosulfate | 湖南大学 | 2023-12-05 | — | — | CN | disclosed |