Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849709 | 0.77 | LMNA (0.38) | KCNH3NCF1LMNAALDH1A1MAPT | |
| SCHEMBL28564265 | 0.74 | THRB (0.52) | KCNH3NCF1LMNAALDH1A1MAPT | |
| SCHEMBL20835959 | 0.74 | GAA (0.42) | KCNH3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL31313551 | 0.73 | HTR7 (0.38) | KCNH3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL25298229 | 0.73 | KCNH3 (0.48) | KCNH3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL28572444 | 0.72 | GAA (0.47) | KCNH3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL19297416 | 0.72 | NPC1 (0.56) | KCNH3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL30288272 | 0.72 | ALDH1A1 (0.44) | KCNH3LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL21928897 | 0.70 | DRD4 (0.46) | KCNH3ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL3753220 | 0.69 | EGLN2 (0.44) | KCNH3LMNAALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343056-A | Pyridopyrrole derivatives and their use in medicine | 广东东阳光药业股份有限公司 | 2024-01-05 | — | — | CN | disclosed |