SCHEMBL29136495

SCHEMBL29136495

COC(=O)c1cc(O)c(Cc2ccccc2)c(OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
HPGD P15428 2/20 0.58
HSP90AA1 P07900 3/20 0.50
CNR2 P34972 1/20 0.47
XDH P47989 2/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
NFKB1 P19838 1/20 0.46
GFER P55789 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
FUT7 Q11130 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PTPN11 Q06124 1/20 0.45
PTPN1 P18031 1/20 0.45
TSHR P16473 1/20 0.45
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16143289 0.91 HPGD (0.52) LMNAHPGDHSP90AA1POLBL3MBTL1
SCHEMBL18397048 0.80 HPGD (0.82) LMNAHPGDKDM4EGAATSHR
SCHEMBL15366480 0.78 LMNA (0.54) LMNAHPGDHSP90AA1KDM4ENFKB1
SCHEMBL29136465 0.77 LMNA (0.61) LMNAHPGDCNR2TDP1L3MBTL1
SCHEMBL8993073 0.77 MAPT (0.51) LMNAHPGDTSHRCYP4F2CYP4A11
SCHEMBL21738207 0.77 HPGD (0.77) LMNAHPGDKDM4EPTPN1TPMT
SCHEMBL24856262 0.77 MAPT (0.51) LMNAHPGDCNR2XDHKDM4E
SCHEMBL4874871 0.76 LMNA (0.76) LMNAHPGDXDHKDM4EPOLB
SCHEMBL30102539 0.76 LMNA (0.76) LMNAHPGDXDHKDM4EPOLB
SCHEMBL2140229 0.76 LMNA (0.58) LMNAHPGDKDM4ETSHRCYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362192-A PET radioactive tracer for imaging glycine transporter Glyt2 浙江颐核医疗科技有限公司 2024-01-09 CN disclosed