Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682387 | 0.65 | AGTR1 (0.43) | AGTR1LTB4R2ACHEPPARGCNR2 | |
| SCHEMBL8305889 | 0.64 | ACHE (0.37) | AGTR1LTB4R2ACHEPPARGCNR2 | |
| SCHEMBL7649207 | 0.63 | ACHE (0.47) | AGTR1LTB4R2ACHEPPARGCNR2 | |
| SCHEMBL5411252 | 0.63 | AGTR1 (0.43) | AGTR1LTB4R2ACHEPPARGCNR2 | |
| SCHEMBL9402468 | 0.63 | ACHE (0.44) | AGTR1LTB4R2ACHEPPARGCNR2 | |
| SCHEMBL2692039 | 0.62 | PPARG (0.53) | AGTR1ACHEPPARGAGTR2 | |
| SCHEMBL9846028 | 0.62 | ESR2 (0.56) | ACHEITGB1ITGA4PPARGCNR2 | |
| SCHEMBL29598156 | 0.62 | ACHE (1.00) | AGTR1LTB4R2ACHEAGTR2 | |
| SCHEMBL1316335 | 0.62 | ACHE (1.00) | AGTR1LTB4R2ACHEAGTR2 | |
| SCHEMBL4253889 | 0.61 | HSD17B10 (0.58) | AGTR1ACHEPPARGAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835689-B | Solvent-free method for preparing irbesartan | 浙江金立源药业有限公司 | 2024-01-02 | — | — | CN | disclosed |