Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143007 | 0.85 | MAPT (0.45) | MEN1KMT2ARXFP1LMNANPC1 | |
| Trifluoroacetic Acid SCHEMBL7417053 | 0.77 | ITGB3 (0.53) | KLK1KLK5PLGPLAUPLAT | |
| Trifluoroacetic Acid SCHEMBL30725604 | 0.77 | KLK1 (0.51) | KLK1KLK5MEN1KMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL17894404 | 0.77 | EPHX2 (0.53) | KLK1KLK5LMNARAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL17894363 | 0.77 | NPC1 (0.52) | KLK1KLK5MEN1KMT2ANPC1 | |
| SCHEMBL24891830 | 0.77 | KMT2A (0.64) | MEN1KMT2ALMNANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL29803776 | 0.75 | MLYCD (0.49) | KLK1KLK5MEN1KMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL17894392 | 0.75 | LTA4H (0.61) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL17894498 | 0.75 | NR4A2 (0.51) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29142990 | 0.74 | CXCR2 (0.55) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447375-A | Guanidine compound, preparation method and application thereof | 中国医学科学院药物研究所 | 2024-01-26 | — | — | CN | disclosed |