SCHEMBL29149342

SCHEMBL29149342

FC(F)c1ccc(CI)cc1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 2/20 0.38
PGK2 P07205 2/20 0.38
DAO P14920 1/20 0.36
NOTUM Q6P988 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.31
MBOAT4 Q96T53 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15018988 0.79 DAO (0.40) PGK1PGK2DAONOTUMMRGPRX4
SCHEMBL2265906 0.78 TSHR (0.41) PGK1PGK2
SCHEMBL662302 0.76 PGK1 (0.38) PGK1PGK2DAONOTUMMRGPRX4
SCHEMBL649682 0.76 ALDH1A1 (0.37)
SCHEMBL1659677 0.76 DAO (0.41) PGK1PGK2DAONOTUMMRGPRX4
SCHEMBL17092743 0.74 CA1 (0.38) PGK1PGK2DAOMRGPRX4MBOAT4
SCHEMBL21777546 0.74 LOXL2 (0.52)
SCHEMBL172620 0.74 IDO1 (0.52)
SCHEMBL472558 0.74 TSHR (0.43) PGK1PGK2DAOMRGPRX4
SCHEMBL3714185 0.74 TSHR (0.54) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447298-A Synthetic method of halogenated methyl difluoromethyl benzene 上海泰坦科技股份有限公司 2024-01-26 CN disclosed