Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2076854 | 0.76 | KDR (0.48) | KDRIKBKB | |
| SCHEMBL2076282 | 0.75 | ACHE (0.39) | JAK3JAK2JAK1 | |
| SCHEMBL2076844 | 0.73 | L3MBTL1 (0.40) | KDRJAK3JAK2JAK1IKBKB | |
| SCHEMBL2076440 | 0.65 | TGFBR1 (0.33) | JAK3IKBKB | |
| SCHEMBL174293 | 0.65 | ADORA2A (0.45) | IKBKB | |
| SCHEMBL2078208 | 0.64 | IKBKB (0.41) | JAK3JAK2JAK1IKBKB | |
| SCHEMBL26406187 | 0.64 | ADORA3 (0.41) | JAK3JAK2JAK1 | |
| SCHEMBL2078237 | 0.64 | BTK (0.33) | — | |
| SCHEMBL31226879 | 0.64 | ACHE (0.41) | JAK3JAK2JAK1 | |
| SCHEMBL6233600 | 0.64 | ACHE (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242080-A | Boron-containing pyrazole compounds, compositions comprising the same, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2023-12-15 | — | — | CN | disclosed |