Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155492 | 0.90 | AKT1 (0.43) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL29155485 | 0.86 | BCL2A1 (0.45) | TAS2R14NPC1RAB9AALDH1A1LIMK2 | |
| SCHEMBL29155493 | 0.85 | ACHE (0.53) | TAS2R14GPR52NPC1RAB9AALDH1A1 | |
| SCHEMBL29083741 | 0.84 | TAS2R14 (0.50) | TAS2R14GPR52NPC1RAB9AALDH1A1 | |
| SCHEMBL8743153 | 0.78 | GSTO1 (0.47) | NPC1RAB9AALDH1A1LMNATRPM8 | |
| SCHEMBL29083717 | 0.78 | TAS2R14 (0.47) | TAS2R14NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28470557 | 0.76 | HSD11B1 (0.50) | KMT2AMEN1LMNA | |
| SCHEMBL29083719 | 0.74 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31397799 | 0.74 | TAS2R14 (0.46) | TAS2R14GPR52NPC1RAB9AALDH1A1 | |
| SCHEMBL29155502 | 0.74 | ALDH1A1 (0.44) | GPR52NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024400-A | Preparation method of aromatic heterocyclic ring-containing enamide derivative | 赣南师范大学 | 2023-11-10 | — | — | CN | disclosed |