SCHEMBL29155485

SCHEMBL29155485

C=CC(=O)N(Cc1ccccc1)C(=C)c1ccc(F)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCL2A1 Q16548 1/20 0.45
TAS2R14 Q9NYV8 2/20 0.44
AGER Q15109 2/20 0.43
MTNR1A P48039 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
ACKR3 P25106 1/20 0.41
TMEM97 Q5BJF2 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LIMK2 P53671 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29155492 0.90 AKT1 (0.43) NPC1RAB9ATDP1
SCHEMBL29155486 0.86 TAS2R14 (0.44) TAS2R14NPC1RAB9AALDH1A1LIMK2
SCHEMBL29083762 0.83 TAS2R14 (0.49) TAS2R14AGERMTNR1AL3MBTL1ACKR3
SCHEMBL29155493 0.83 ACHE (0.53) BCL2A1TAS2R14L3MBTL1SIGMAR1NPC1
SCHEMBL8743153 0.78 GSTO1 (0.47) BCL2A1NPC1RAB9ATDP1ALDH1A1
SCHEMBL28470557 0.76 HSD11B1 (0.50) L3MBTL1TDP1
SCHEMBL29155502 0.74 ALDH1A1 (0.44) L3MBTL1NPC1RAB9AALDH1A1
SCHEMBL31397792 0.73 TAS2R14 (0.45) TAS2R14AGERMTNR1AL3MBTL1ACKR3
SCHEMBL29155484 0.71 TRPM8 (0.41) MTNR1AALDH1A1
SCHEMBL295841 0.71 LMNA (0.53) NPC1RAB9ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024400-A Preparation method of aromatic heterocyclic ring-containing enamide derivative 赣南师范大学 2023-11-10 CN disclosed