Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.70 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958539 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL1150651 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL10001722 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL3958542 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL464850 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL6128484 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL12381602 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| SCHEMBL2637678 | 1.00 | EPHX1 (0.70) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL21331609 | 0.98 | EPHX1 (0.68) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL291654 | 0.98 | EPHX1 (0.68) | EPHX1TRPM8TRPA1SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170368521-A1 | METHOD FOR STORING COOLING AGENTS | SYMRISE AG (DE) | 2017-12-28 | — | — | US | disclosed |
| US-20170216802-A1 | Process for the Production of Solid Cooling Agents | SYMRISE AG (DE) | 2017-08-03 | — | — | US | disclosed |
| WO-2012151106-A2 | INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS | RENESSENZ, LLC (US) | 2012-11-08 | — | — | WO | disclosed |
| US-20120283469-A1 | INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS | PINOVA HOLDINGS, INC | 2012-11-08 | — | — | US | disclosed |
| US-20120116113-A1 | PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS | RENESSENZ LLC | 2012-05-10 | — | — | US | disclosed |
| EP-2450337-A2 | Process for making neo-enriched p-menthane compounds | Renessenz LLC (US) | 2012-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283469-A1 | INTERCONVERSION BETWEEN ISOMERIC P-MENTHANE-3-CARBOXYLIC ACIDS | ME1, TASP1, MNS1 | EPHX1 255/4885TRPM8 1087/4885TRPA1 781/4885 |
| US-20120116113-A1 | PROCESS FOR MAKING NEO-ENRICHED p-MENTHANE COMPOUNDS | ME3, MDH2, ME2 | EPHX1 238/4885TRPM8 571/4885TRPA1 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.