Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168454 | 0.90 | PKM (0.31) | KDM4E | |
| SCHEMBL30853312 | 0.89 | PARP1 (0.31) | — | |
| SCHEMBL27186177 | 0.80 | PDK2 (0.36) | KDM4EALDH1A1HPGDNPSR1NR4A2 | |
| SCHEMBL29168391 | 0.73 | KRAS (0.33) | — | |
| SCHEMBL29168393 | 0.73 | KRAS (0.33) | — | |
| SCHEMBL27186349 | 0.72 | NR4A2 (0.40) | KDM4EALDH1A1HPGDNPSR1NR4A2 | |
| SCHEMBL27186983 | 0.72 | KDM4E (0.38) | AXLKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL27186283 | 0.70 | PRKAB2 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL27186424 | 0.69 | GCK (0.36) | — | |
| SCHEMBL27186192 | 0.68 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDNPSR1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |